Diltiazem hydrochloride: New technologies and evolution of diltiazem
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چکیده
منابع مشابه
Development and evaluation of microporous osmotic tablets of diltiazem hydrochloride
Microporous osmotic tablet of diltiazem hydrochloride was developed for colon targeting. These prepared microporous osmotic pump tablet did not require laser drilling to deliver the drug to the specific site of action. The tablets were prepared by wet granulation method. The prepared tablets were coated with microporous semipermeable membrane and enteric polymer using conventional pan coating p...
متن کاملSelective spectrophotometric determination of diltiazem hydrochloride in tablets.
Diltiazem hydrochloride (Ia) is an important coronary vasodilator drug of the calcium channel-blocker type, used in therapy of heart disease and hypertension. The compound is (+)-5-[2-(dimethylamino)ethyl]-c&, 2,3dihydro3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate monohydrochloride. The drug and its tablet formulations are official in the USP [l] wherein they are estimated...
متن کاملDevelopment of Gastro Retentive Floating Matrix Tablets of Diltiazem Hydrochloride
Cervicofacial hemangiomas treated from January 2001 to December 2009 was clinically evaluated. This retrospective clinical study consisted of 42 females and 20 males with the age ranged from 20 days to 55 years. The lesions were present with-in first month in 45 patients (72.6%). Two patterns of tumor growth were evident: focal and diffuse. There were 59 focal hemangiomas (80.8%) and 14 diffuse...
متن کاملDesign of Gastro Retentive Drug Delivery System of Diltiazem Hydrochloride
L. K. Omray Ravishankar College of Pharmacy, Bhopal E.mail: [email protected] Abstract Gastro retentive drug delivery system of diltiazem hydrochloride was designed and evaluated for its effectiveness for the management of mild to moderate hypertension. Gastro retentive drug delivery system were prepared using polyvinyl alcohol and sodium carboxy methyl cellulose as the polymers and sodium...
متن کاملIn vitro Release Kinetics Study of Diltiazem Hydrochloride from Wax and Kollidon SR Based Matrix Tablets
Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2009
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960261605